Symbol: RAD51 Name: RADiation sensitive 51 Entrez gene ID: 856831 Ensembl gene ID: YER095W Species: Yeast (Taxid: 4932) Functional description: Rad51p; Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein [Source:SGD;Acc:S000000897] [Ensembl] Observation: Rad51 mutations result in a 40% reduced mean replicative lifespan in strain PSY316 [10207108]. RAD51 is required for gene conversion, but not for repair of an HO-induced double-stranded break [8692957]. RAD51 deletion decreases formation of extrachromosomal rDNA circles [10207108]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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