Symbol: RAD27 Entrez gene ID: 853747 Ensembl gene ID: YKL113C Species: Yeast (Taxid: 4932) Functional description: Rad27p; 5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family [Source:SGD;Acc:S000001596] [Ensembl] Observation: Deletion of RAD27 results in signs of premature aging and approximately 60% reduction in mean replicative lifespan [12024027]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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