Symbol: pgl-1 Name: P GranuLe abnormality Entrez gene ID: 177461 Ensembl gene ID: ZK381.4 Species: Worm (Taxid: 6239) Functional description: maternally provided protein maintains a population of proliferating germ cells and zygotic expression is required for correct oogenesis. Predicted to bind RNA. [UniProt] Observation: pgl-1(bn101) mutant animals that are sterile have a approximately 35% longer lifespan. In contrast, fertile pgl-1(bn101) animals have a wild-type lifespan [11799246]. PGL-1 is required for fertility and proliferation of germ line cells [9741628]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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