pgl-1

Symbol: pgl-1
Name: P GranuLe abnormality
Entrez gene ID: 177461
Ensembl gene ID: ZK381.4
Species: Worm (Taxid: 6239)

Functional description:
maternally provided protein maintains a population of proliferating germ cells and zygotic expression is required for correct oogenesis. Predicted to bind RNA. [UniProt]

Observation:

pgl-1(bn101) mutant animals that are sterile have a approximately 35% longer lifespan. In contrast, fertile pgl-1(bn101) animals have a wild-type lifespan [11799246].

PGL-1 is required for fertility and proliferation of germ line cells [9741628].



Interventions:
  • pgl-1 mutation +35%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • pgl-1 (6239)
  • pgl-3 (6239)



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