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Symbol: pfn-2 Name: ProFiliN Entrez gene ID: 180808 Ensembl gene ID: F35C8.6 Species: Worm (Taxid: 6239) Functional description: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity). [UniProt] Observation: RNA interference extended lifespan. Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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