Denigma

par-5

Symbol: par-5
Name: abnormal embryonic PARtitioning of cytoplasm
Entrez gene ID: 178113
Ensembl gene ID: M117.2
Species: Worm (Taxid: 6239)

Functional description:
Protein PAR-5; 14-3-3-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:P41932] [Ensembl]

Observation:

RNA interference slightly shortens lifespan and suppresses life-extension by sir-2.1 overexpression but not by daf-2 mutants. Overexpression extends lifespan by 30%, but is suppressed by RNA interference of daf-16.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • YWHAZ (9606)
  • YWHAZ (9598)
  • YWHAZ (9615)
  • YWHAZ (9913)
  • Ywhaz (10090)
  • Ywhaz (10116)
  • YWHAZ (9031)
  • ywhaqb (7955)
  • ywhaqa (7955)
  • 14-3-3zeta (7227)
  • AgaP_AGAP007643 (7165)
  • par-5 (6239)
  • ftt-2 (6239)

    • Orthologs
  • BMH1 (4932)
  • BMH2 (4932)
  • BMH1 (4932)
  • BMH2 (4932)



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