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Symbol: osm-3 Name: OSMotic avoidance abnormal Entrez gene ID: 177141 Ensembl gene ID: M02B7.3 Species: Worm (Taxid: 6239) Functional description: Encodes a kinesin motor domain; May have a role during neurogenesis and axonal transport. [UniProt] Observation: Recessive osm-3 loss-of-function alleles can extend lifespan by 100%, which is suppressed by gonad ablation but not germ line ablation [10617200]. osm-3 mutants do not form dauers in response to starvation and have defective cilia [1732156] as well as are defective in chemosensory response and chemotaxis [7714894]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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