osm-1

Symbol: osm-1
Name: OSMotic avoidance abnormal
Entrez gene ID: 181715
Ensembl gene ID: T27B1.1
Species: Worm (Taxid: 6239)

Functional description:
Required for the maintenance and formation of chemosensory cilia that detect chemosensory cues. [UniProt]

Observation:

Loss-of-function mutation in osm-1 increases lifespan by up to 40% [10617200].

osm-1 mutants are defective in chemotaxis, dye filling and daufer formation, have short axonemes and ectopicassembly of ciliary structures and microtubules in many sensory neurons [2428682].



Interventions:
  • osm-1 mutation +40%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • IFT172 (9606)
  • IFT172 (9615)
  • IFT172 (9913)
  • Ift172 (10090)
  • IFT172 (9031)
  • ift172 (7955)
  • osm-1 (7227)
  • AgaP_AGAP005330 (7165)
  • osm-1 (6239)



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