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Symbol: odr-3 Name: ODoRant response abnormal Entrez gene ID: 179806 Ensembl gene ID: C34D1.3 Species: Worm (Taxid: 6239) Functional description: G Protein, Alpha subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. This specific G-alpha subunit plays an important role in olfaction and in cilia morphogenesis. Involved in chemotactic responses to attractants diacetyl, pyrazine, 2,4,5- trimethylthiazole, benzaldehyde, isoamyl alcohol, butanone and 2,3-pentanedione. Displays a redundant function with gpa-3 in chemotactic responses. Involved in avoidance responses to copper, sodium dodecyl sulfate and linoleic acid. Involved in osmotic avoidance and mechanosensory responses. Involved in specifying fan-like morphology of cilia of head sensory neurons AWC. [UniProt] Observation: Loss-of-function mutation extended mean lifespan by 10-30% but not maximum lifespan. Life-extension was dependent on daf-16 but cumulative with daf-2 mutations. Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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