NDI1

Symbol: NDI1
Name: NADH Dehydrogenase Internal 1
Entrez gene ID: 854919
Ensembl gene ID: YML120C
Species: Yeast (Taxid: 4932)

Functional description:
Mitochondrial electron transport chain; Ndi1p; NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I; phosphorylated; homolog of human AMID [Source:SGD;Acc:S000004589] [Ensembl]

Observation:

Deletion of NDI1 results in chronological lifespan extension [16436509].



Interventions:
  • NDI1 deletion

  • Assays: Chronological Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SPBC947.15c (4896)
  • NDI1 (4932)
  • KLLA0C06336g (28985)
  • AGOS_AFR447C (33169)

  • Orthologs
  • NDE1 (4932)
  • NDE2 (4932)



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