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Symbol: nac-3 Name: NADC (Na+-coupled dicarboxylate transporter) family Entrez gene ID: 176429 Ensembl gene ID: K08E5.2 Species: Worm (Taxid: 6239) Functional description: High-affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Plays a role in the regulation of life span. [UniProt] Observation: RNA interference knockdown of nac-3 leads to an 15% increase in average lifespan. Assays: Organismal Lifespan Mean: +15 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Edit \ Update (Admin) | Delete |
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