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Symbol: mep-1 Name: Mog interacting, Ectopic P granules Entrez gene ID: 178074 Ensembl gene ID: M04B2.1 Species: Worm (Taxid: 6239) Functional description: Post-transcriptional gene regulation; Has a broad role in development, specifically in the genetic pathway SynMuvB that negatively regulates specification of the vulval cell fate. Required for fem-3 3'-UTR-mediated repression in the regulation of the sperm/oocyte switch. Acts by regulating the translation of fem-3 mRNA, by binding to its 3'- UTR. [UniProt] Observation: RNA interference results in a 39% decrease in median lifespan in daf-2 mutants, 14% decrease in lifespan in daf-2/daf-16 double mutants and 8% decrease in median lifespan in a wild-type background. Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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