|
Symbol: lmn-1 Name: nuclear LaMiN Entrez gene ID: 172687 Ensembl gene ID: DY3.2 Species: Worm (Taxid: 6239) Functional description: Major component of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Provides a framework for the nuclear envelope and probably also interacts with chromatin. Essential to maintain the shape and integrity of the nucleus, and for DNA replication. Involved in spatial organization of nuclear pore complexes. It is not a target for ced-3 during apoptosis, suggesting that lamin cleavage is not essential for apoptosis in C.elegans. [UniProt] Observation: Deletion resulted in a shortened lifespan. Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
Comment on This Data Unit