lin-2

Symbol: lin-2
Name: abnormal cell LINeage
Entrez gene ID: 181400
Ensembl gene ID: F17E5.1
Species: Worm (Taxid: 6239)

Functional description:
Encodes a protein belonging to the membrane associated guanylate kinase (MAGUK); May play a structural role in the induction of the vulva. May be required for the localization of signal transduction molecules (such as let-23 receptor) to either the basal membrane domain or the cell junctions. [UniProt]

Observation:

RNA interference extends lifespan.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • CASK (9606)
  • CASK (9615)
  • CASK (9913)
  • Cask (10090)
  • Cask (10116)
  • CASK (9031)
  • caskb (7955)
  • Caki (7227)
  • AgaP_AGAP001683 (7165)
  • lin-2 (6239)



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