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Symbol: ldb-1 Name: LIM domain Binding Protein Entrez gene ID: 181292 Ensembl gene ID: F58A3.1 Species: Worm (Taxid: 6239) Functional description: Protein LDB-1; LIM domain Binding Protein family member (ldb-1) [Source:RefSeq peptide;Acc:NP_509844] [Ensembl]; ldb-1 encodes an Ldb/NLI/Clim member of the nuclear LIM binding protein family that affects coordinated locomotion, vulval development, mechanosensation, and growth of larvae and is required for transcriptional activation of mec-2; can interact with MEC-3 to activate transcription using yeast two-hybrid assays and is expressed in all neurons, vulval cells, gonadal sheath cells, and in some body muscle cells. [WormBase] Observation: RNA interference resulted in decreased lifespan and earlier accumulation of lipofuscin. Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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