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Symbol: baf-1 Name: Barrier to Autointegration Factor 1 Entrez gene ID: 176330 Ensembl gene ID: B0464.7 Species: Worm (Taxid: 6239) Functional description: DNA-binding protein which plays an essential role in nuclear envelope formation. Required for normal chromosome segregation during mitosis. Associates with the nuclear lamina via its interaction with LEM domain containing proteins emr-1 and lem- 2. [UniProt] Observation: RNA interference of baf-1 decreases median lifespan by 28% in daf-2 mutants [18006689]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Note: Does baf-1 mutation also affect wild-type lifespan? Edit \ Update (Admin) | Delete |
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