Denigma: Factor

ife-1

Symbol: ife-1
Name: Initiation Factor 4E (eIF4E) family
Entrez gene ID: 176755
Ensembl gene ID: F53A2.6
Species: Worm (Taxid: 6239)

Functional description:
A scaffold protein for translation initiation factors; disulfide bonds change the width and depth of the cap-binding cavity determining selectivity to mRNA caps. Required for progression through meiotic divisions during spermatogenesis and for the production of viable sperm. It is not required during oogenesis. [UniProt]

Observation:

RNA interference increased maximum lifespan by 7-10%.

Assays:

Classification:

Aging Relevance Analysis/Source:

GenAge