Symbol: HAT2 Name: Histone AcetylTransferase 2 Entrez gene ID: 856654 Ensembl gene ID: YEL056W Species: Yeast (Taxid: 4932) Functional description: Hat2p; Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing [Source:SGD;Acc:S000000782] [Ensembl] Observation: HAT2 deletion mutants have an by 30% extended mean replicative lifespan. A hat2 mutant or a hat1hat2 double mutant, but not a hat1 mutant, have an extended lifespan [16023114]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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