Symbol: gst-10 Name: Glutathione S-Transferase Entrez gene ID: 178725 Ensembl gene ID: Y45G12C.2 Species: Worm (Taxid: 6239) Functional description: Conjugation of the lipid peroxidation product 4-hydroxynonenal (4-HNE); Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Responsible for approximately one-third of 4-hydroxy-2-nonenal conjugation. [UniProt] Observation: Overexpression resulted in transgenic animals with enhanced stress resistance and increased lifespan by 13-22%. Assays: Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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