gst-10

Symbol: gst-10
Name: Glutathione S-Transferase
Entrez gene ID: 178725
Ensembl gene ID: Y45G12C.2
Species: Worm (Taxid: 6239)

Functional description:
Conjugation of the lipid peroxidation product 4-hydroxynonenal (4-HNE); Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Responsible for approximately one-third of 4-hydroxy-2-nonenal conjugation. [UniProt]

Observation:

Overexpression resulted in transgenic animals with enhanced stress resistance and increased lifespan by 13-22%.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • GSTP1 (9606)
  • GSTP1 (9598)
  • LOC476005 (9615)
  • LOC475191 (9615)
  • LOC480844 (9615)
  • LOC611366 (9615)
  • LOC480657 (9615)
  • GSTP1 (9913)
  • Gstp2 (10116)
  • Gstp1 (10116)
  • gstp1 (7955)
  • gstp2 (7955)
  • gst-1 (6239)
  • gst-25 (6239)
  • gst-10 (6239)
  • gst-41 (6239)
  • gst-23 (6239)
  • Y45G12C.3 (6239)
  • F56A4.4 (6239)
  • F56A4.3 (6239)



  • Edit \ Update (Admin) | Delete

    Comment on This Data Unit