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Symbol: GLN3 Name: GLutamiNe metabolism 3 Entrez gene ID: 856763 Ensembl gene ID: YER040W Species: Yeast (Taxid: 4932) Functional description: Gln3p; Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source [Source:SGD;Acc:S000000842] [Ensembl] Observation: Deletion of GLN3 extends chronological lifespan [16418483]. GLN3 deletion decreases replicative lifespan by 20% in the alpha strain [19030232]. GLN3 deletion in the vineyard strain dramatically shortens chronological lifespan, while extends that of the laboratory strain [21901113]. Interventions: Assays: Replicative Lifespan Chronological Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Note: Is it a gerontogene or aging-suppressor. Edit \ Update (Admin) | Delete |
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