aakb-1

Symbol: aakb-1
Name: AMP-Activated Kinase Beta subunit 1
Entrez gene ID: 181492
Ensembl gene ID: F55F3.1
Species: Worm (Taxid: 6239)

Functional description:
Protein involved in Snf1 protein kinase complex assembly; Protein AAKB-1; AMP-Activated Kinase Beta subunit family member (aakb-1) [Source:RefSeq peptide;Acc:NP_510298] [Ensembl]; aakb-1 encodes one of two C. elegans AMP kinase (AMPK) beta regulatory subunits. [WormBase]

Observation:

RNA interference of aakb-1 results in decreased lifespan and earlier accumulation of lipofuscin [16673436].



Interventions:
  • aakb-1 RNAi

  • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PRKAB2 (9606)
  • PRKAB2 (9598)
  • PRKAB2 (9615)
  • PRKAB2 (9913)
  • Prkab2 (10090)
  • Prkab2 (10116)
  • PRKAB2 (9031)
  • zgc:172285 (7955)
  • aakb-2 (6239)
  • aakb-1 (6239)
  • SPCC1919.03c (4896)
  • SIP2 (4932)
  • GeneID:2685103 (148305)
  • NCU03837 (5141)
  • AT5G21170 (3702)
  • Os05g0491200 (4530)



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