XRCC6

Symbol: XRCC6
Name: X-ray repair complementing defective repair in Chinese hamster cells 6
Entrez gene ID: 2547
Ensembl gene ID: ENSG00000196419
Species: Human (Taxid: 9606)


Observation:

The single-nucleotide polymorphism in rs132793 in XRCC6 has significant effect on telomere length, but it is not associated with longevity [21972126].



Assays: Organismal Lifespan

Longevity Associated Variants:
  • rs132793 0.74 [21972126]

  • Classification:
  • No Age Effect


  • Type:
  • Gene
  • Protein coding

    References:
  • 21972126: Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • XRCC6 (9606)
  • XRCC6 (9598)
  • XRCC6 (9615)
  • XRCC6 (9913)
  • Xrcc6 (10090)
  • Xrcc6 (10116)
  • XRCC6 (9031)
  • xrcc6 (7955)
  • Irbp (7227)
  • AgaP_AGAP002690 (7165)
  • cku-70 (6239)
  • pku70 (4896)
  • YKU70 (4932)
  • KLLA0C06226g (28985)
  • GeneID:2679155 (148305)
  • NCU08290 (5141)
  • KU70 (3702)
  • Os07g0184900 (4530)

  • Inparanoids
  • ENSP00000353192 (9606)
  • ENSMUSP00000068559 (10090)
  • ENSRNOP00000008819 (10116)
  • ENSMMUP00000036966 (9544)
  • YMR284W (4932)
  • SPCC126.02c (4896)
  • ENSP00000353192 (9606)



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