erm-1

Symbol: erm-1
Name: Ezrin/Radixin/Moesin
Entrez gene ID: 172174
Ensembl gene ID: C01G8.5
Species: Worm (Taxid: 6239)

Functional description:
Protein ERM-1; Ezrin/Radixin/Moesin family member (erm-1) [Source:RefSeq peptide;Acc:NP_491559] [Ensembl]; The erm-1 gene encodes an ortholog of the ERM family of cytoskeletal linkers with approximately equal similarity to ezrin, radixin and moesin. It has a somewhat more distant homology to human merlin/schwannomin (NF2), which when mutated leads to neurofibromatosis, type 2 (OMIM:101000). [WormBase]

Observation:

RNA interference in adulthood resulted in a 15% mean lifespan extension.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • MSN (9606)
  • MSN (9615)
  • MSN (9913)
  • Msn (10090)
  • Msn (10116)
  • msna (7955)
  • Moe (7227)
  • AgaP_AGAP000562 (7165)
  • erm-1 (6239)



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