Denigma

Akt1

Symbol: Akt1
Name: CG4006 gene product from transcript CG4006-RA
Entrez gene ID: 41957
Ensembl gene ID: FBgn0010379
Species: Fly (Taxid: 7227)


Observation:

RNA interference of Akt1 in intestinal stem cells, results in impaired regeneration of the intestinal epithelium and a short lifespan. In males and females on mean lifespan is 11.4% and 7.4% lower [20976250].



Interventions:
  • Akt1 RNAi -11.4 to -7.4%

    • Assays: Organismal Lifespan
    Mean: -7.4 to -11.4

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


    • Type:
  • Gene
  • Protein coding

    References:
  • 20976250: Lifespan extension by preserving proliferative homeostasis in Drosophila.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • AKT3 (9606)
  • AKT3 (9615)
  • AKT3 (9913)
  • Akt3 (10090)
  • Akt3 (10116)
  • AKT3 (9031)
  • akt3 (7955)
  • Akt1 (7227)

    • Inparanoids
  • FBpp0082682 (7227)
  • ENSMUSP00000106790 (10090)
  • ENSRNOP00000025303 (10116)
  • ENSMMUP00000026292 (9544)
  • ENSP00000263826 (9606)



    • Edit \ Update (Admin) | Delete

    Comment on This Data Unit