Rab3b

Symbol: Rab3b
Name: RAB3B, member RAS oncogene family
Alias: Ras-related protein Rab-3B
Entrez gene ID: 81755
Ensembl gene ID: ENSRNOG00000008001
Species: Rat (Taxid: 10116)

Function:
May play a role in secretory granule function and exocytosis in pancreatic acinar cells [RGD, Feb 2006]

Observation:

Rab3b is transcriptional upregulated in the cerebral cortex at the age 28 months under different longevity conditions such as under dietary restriction (DR) as well as in feeding switch regimens that result in extended lifespan, like early age switch to DR as well as the reverse switch under the influence of the DR-mimetic α-lipoic acid (i.e. DR switched to ad libitum+ lipoic acid) [Shona et al. 2013].



Assays: Organismal Lifespan

Classification:
  • Longevity-Associated
  • Longevity-Differential
  • Longevity-Induced
  • DR-Associated
  • DR-Differential
  • DR-Induced


  • Type:
  • Protein coding

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • RAB3B (9606)
  • RAB3B (9598)
  • RAB3B (9615)
  • RAB3B (9913)
  • Rab3b (10090)
  • Rab3b (10116)
  • RAB3B (9031)
  • rab3b (7955)

  • Inparanoids
  • ENSRNOP00000010645 (10116)
  • ENSRNOP00000010645 (10116)
  • ENSRNOP00000010645 (10116)



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