Sphkap

Symbol: Sphkap
Name: A-kinase anchor protein SPHKAP
Entrez gene ID: 316561
Ensembl gene ID: ENSRNOG00000016388
Species: Rat (Taxid: 10116)


Observation:

Sphkap is transcriptional downregulated in the cerebral cortex at the age 28 months under different longevity conditions such as under dietary restriction (DR) as well as in feeding switch regimens that result in extended lifespan, like early age switch to DR as well as the reverse switch under the influence of the DR-mimetic α-lipoic acid (i.e. DR switched to ad libitum+ lipoic acid) [Shona et al. 2013].



Assays: Organismal Lifespan

Classification:
  • Longevity-Associated
  • Longevity-Differential
  • Longevity-Suppressed
  • DR-Associated
  • DR-Differential
  • DR-Suppressed


  • Type:
  • Protein coding

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SPHKAP (9606)
  • SPHKAP (9598)
  • SPHKAP (9615)
  • SPHKAP (9913)
  • Sphkap (10090)
  • Sphkap (10116)
  • SPHKAP (9031)
  • sphkap (7955)



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