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Symbol: egm Name: enigma Entrez gene ID: 36242 Ensembl gene ID: FBgn0086712 Species: Fly (Taxid: 7227) Functional description: Mitochondrial protein involved in lipid metabolism; Enigma; Enigma [Source:FlyBase gene name;Acc:FBgn0086712] [Ensembl]; The gene Enigma is referred to in FlyBase by the symbol Dmel\Egm (CG9006, FBgn0086712). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: long-chain-acyl-CoA dehydrogenase activity. There is experimental evidence that it is involved in the biological process: response to oxidative stress; multicellular organism reproduction; compound eye morphogenesis. 8 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; wing disc; embryonic/larval fat body; imaginal disc. It has one annotated transcript and one annotated polypeptide. Protein features are: Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA dehydrogenase/oxidase; Acyl-CoA dehydrogenase/oxidase C-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-CoA oxidase/dehydrogenase, type 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes. [FlyBase] Observation: Mutation in egm confers resistance to oxidative stress and extends the lifespan [16434470]. Interventions: Assays: Organismal Lifespan Classification: References: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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