egl-45

Symbol: egl-45
Name: EGg Laying defective
Entrez gene ID: 176094
Ensembl gene ID: C27D11.1
Species: Worm (Taxid: 6239)

Functional description:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity). [UniProt]

Observation:

RNA interference in adulthood extended mean lifespan by 52%.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • EIF3A (9606)
  • EIF3A (9598)
  • EIF3A (9615)
  • EIF3A (9913)
  • Eif3a (10090)
  • Eif3a (10116)
  • EIF3A (9031)
  • eif3a (7955)
  • eif3s10 (7955)
  • eIF3-S10 (7227)
  • AgaP_AGAP002340 (7165)
  • egl-45 (6239)
  • tif32 (4896)
  • RPG1 (4932)
  • KLLA0C14498g (28985)
  • AGOS_ABL065W (33169)
  • GeneID:2681764 (148305)
  • NCU00040 (5141)
  • EIF3A (3702)
  • Os01g0120800 (4530)



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