Symbol: GH1 Name: Growth hormone 1 Alias: BOS_19247; GH; somatotropin Entrez gene ID: 280804 Ensembl gene ID: ENSBTAG00000017220 Species: Cow Function: Stimulation of growth and proliferation Observation: Transgenic mice overexpressing bovine GH1 are bigger than controls and display early onset of pathological changes in the kidneys such glomerulosis and glomerulonephritis as well as signs of premature aging such as a shortened lifespan, increased astrogliosis, shortened reproductive lifepsan and early onset of age-related changes in cognitive function, hypothalamic neurotransmitter turnover, and plasma corticosterone levels [14583653]. Interventions: Assays: Organismal Lifespan Classification: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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