Denigma

SIRT6

Symbol: SIRT6
Name: sirtuin 6
Entrez gene ID: 51548
Ensembl gene ID: ENSG00000077463
Species: Human (Taxid: 9606)

Function:
NAD-dependent protein deactylase

Observation:

SIRT6 is a critical modulator of cancer metabolism. SIRT6 is selectively downregulated in several cancers. Expression of SIRT6 predicts prognosis of tumor-free survival rates [23217706].



Assays: Organismal Lifespan

Classification:
  • Cancer-Related
  • Tumor-Suppressor


    • References:
  • 23217706: The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • SIRT6 (9606)
  • SIRT6 (9598)
  • SIRT6 (9615)
  • SIRT6 (9913)
  • Sirt6 (10090)
  • Sirt6 (10116)
  • SIRT6 (9031)
  • sirt6 (7955)
  • Sirt6 (7227)
  • AgaP_AGAP001458 (7165)
  • SRT1 (3702)
  • Os04g0271000 (4530)

    • Inparanoids
  • ENSP00000337332 (9606)
  • ENSMUSP00000048971 (10090)
  • ENSRNOP00000008758 (10116)
  • ENSMMUP00000026241 (9544)
  • ENSP00000337332 (9606)



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