Denigma

Prkaa1

Symbol: Prkaa1
Name: Protein kinase, AMP-activated, alpha 1 catalytic subunit
Entrez gene ID: 105787
Ensembl gene ID: ENSMUSG00000050697
Species: Mouse (Taxid: 10090)

Function:
Serine/threonine protein kinase

Observation:

Prkaa1 hosphorylates Cryptochromes and leads to their degradation [19833968].



Assays: Organismal Lifespan

Classification:
  • Clock Modulator


    • References:
  • 19833968: AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PRKAA1 (9606)
  • PRKAA1 (9615)
  • PRKAA1 (9913)
  • Prkaa1 (10090)
  • Prkaa1 (10116)
  • PRKAA1 (9031)
  • prkaa1 (7955)
  • AKIN11 (3702)
  • AKIN10 (3702)
  • Os05g0530500 (4530)

    • Orthologs
  • aak-2 (6239)
  • aak-2 (6239)

    • Inparanoids
  • ENSRNOP00000017626 (10116)
  • ENSMUSP00000063166 (10090)
  • ENSMUSP00000063166 (10090)



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