JAKMIP3

Symbol: JAKMIP3
Name: Janus kinase and microtubule interacting protein 3
Alias: ENSG00000188385
Entrez gene ID: 282973
Species: Human

Observation:

Age-related differential methylation of the genetic marker rs2818384 which is synonymous to the mutation in JAKMIP3 is statistically significant association with age and aging rate. JAKMIP3 has a cis association with the aging differential methylated marker cg05652533 [23177740].

Copy-number variants of JAKMIP3 are associated with glioblastoma [Xiong et al. 2010].

Xiong, M., Dong, H., Siu, H., Peng, G., Wang, Y., and Jin, L. (2010). Genome-Wide Association Studies of Copy Number Variation in Glioblastoma. Proceedings of the 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE), 1–4.



Assays: Organismal Lifespan

Classification:
  • Aging Associated


  • References:
  • 23177740: Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • JAKMIP3 (9606)
  • JAKMIP3 (9913)
  • C10orf39 (9031)
  • LOC100334213 (7955)

  • Inparanoids
  • ENSMUSP00000065675 (10090)
  • ENSRNOP00000023557 (10116)
  • ENSMMUP00000029430 (9544)



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