Denigma

NEK4

Symbol: NEK4
Name: NIMA (never in mitosis gene a)-related kinase 4
Entrez gene ID: 6787
Ensembl gene ID: ENSG00000114904
Species: Human (Taxid: 9606)

Function:
NEK family of kinases plays a key role in cell-cycle regution and cancer [22040655]

Observation:

Age-related differential methylation of the genetic marker rs2230534 which is synonymous to the mutation in NEK4 is statistically significant association with age and aging rate [23177740].



Assays: Organismal Lifespan

Classification:
  • Aging Associated


    • References:
  • 23177740: Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • NEK4 (9606)
  • NEK4 (9598)
  • NEK4 (9615)
  • NEK4 (9913)
  • Nek4 (10090)
  • Nek4 (10116)
  • NEK4 (9031)
  • nek4 (7955)

    • Inparanoids
  • ENSMUSP00000057915 (10090)
  • ENSRNOP00000024296 (10116)
  • ENSMMUP00000023537 (9544)



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