mir-239

Symbol: mir-239
Species: Worm (Taxid: 6239)


Observation:

Mutating mir-239 increases mean and maximum lifespan by 12 and 36%, respectively, whereas overexpressing mir-239 decreases mean and maximum lifespan by 13 and 17 - 33%, respectively [21129974].



Interventions:
  • mir-239 overexpression -13% -17 to -33%
  • mir-239 mutation +11.8% +36.0%

  • Assays: Organismal Lifespan
    Mean: -16.6 to +11.8
    Maximum: -33.3 to +36.0

    Classification:
  • Gerontogene
  • Negative Gerontogene
  • Positive Gerontogene


  • Type:
  • Gene
  • miRNA

    References:
  • 21129974: MicroRNAs both promote and antagonize longevity in C. elegans.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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