SOD2

Symbol: SOD2
Name: superoxide dismutase 2, mitochondrial
Entrez gene ID: 6648
Ensembl gene ID: ENSG00000112096
Species: Human (Taxid: 9606)

Function:
Oxidative stress; free-radical scavenging antioxidant

Observation:

The SOD2 rs2758331 has been correlated with exceptional longevity in a plethora of genetic signatures [22279548].SOD2 was found to be associated with longevity [20003469]. SOD2 was found to be associated with longevity [17903295]. SOD2 was found to be associated with longevity [15621215]. SOD2 was found to be associated with longevity [20003469]. SOD2 was found to be associated with longevity [19428448]. SOD2 was not found to be associated with longevity [9887369]. SOD2 was found to be associated with longevity [22279548]. SOD2 was not found to be associated with longevity [24163049].



Assays: Organismal Lifespan

Longevity Associated Variants:
  • rs4880 0.002 [19428448]
  • rs2758331 2.92563e-05 [22279548]
  • rs4880 0.009 [15621215]
  • rs4880 0.009 [15621215]
  • rs4880 None [9887369]
  • rs5746098 0.355 [20003469]
  • rs6917589 0.741 [24163049]
  • rs2842980 0.689 [24163049]
  • rs7855 0.842 [24163049]
  • rs8031 0.186 [24163049]
  • rs5746141 0.601 [24163049]
  • rs5746136 0.354 [24163049]
  • rs5746133 0.466 [24163049]
  • rs4880 0.552 [24163049]

  • Classification:
  • Longevity-Associated
  • No Age Effect


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SOD2 (9606)
  • SOD2 (9598)
  • SOD2 (9615)
  • SOD2 (9913)
  • Sod2 (10090)
  • Sod2 (10116)
  • SOD2 (9031)
  • sod2 (7955)
  • Sod2 (7227)
  • SOD1 (7165)
  • sod-3 (6239)
  • sod-2 (6239)
  • SPAC1486.01 (4896)
  • SOD2 (4932)
  • KLLA0E03609g (28985)
  • GeneID:2674520 (148305)
  • NCU09560 (5141)
  • MSD1 (3702)
  • Os05g0323900 (4530)

  • Inparanoids
  • ENSP00000356022 (9606)
  • ENSMUSP00000007012 (10090)
  • ENSRNOP00000025794 (10116)
  • YHR008C (4932)
  • SPAC1486.01 (4896)
  • ENSP00000356022 (9606)



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