Denigma

nekl-2

Symbol: nekl-2
Name: NEK (NEver in mitosis Kinase) Like 2
Alias: phi-35
Entrez gene ID: 191199
Ensembl gene ID: ZC581.1
Species: Worm (Taxid: 6239)


Observation:

RNA intereference of nekl-2 decreases lifespan by 24% and suppresses lifespan extension by eat-2 mutation [22829775].



Interventions:
  • nekl-2 RNAi -24%

    • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor
  • DR-Essential


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • nekl-2 (6239)
  • ATNEK5 (3702)
  • nek-1 (5833)

    • Note: Is lifespan-shortening effect of nekl-2 significant?

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