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Symbol: cyc-2.1 Name: CYtochrome C 2.1 Entrez gene ID: 177243 Ensembl gene ID: E04A4.7 Species: Worm (Taxid: 6239) Functional description: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. [UniProt] Observation: RNA interference of cyc-2.1 increases mean lifespan by 80% [17608836]. cyc-2.1 RNAi has no significant effect on lifespan of eat-2 mutants, although CYC-2.1 levels are elevated in eat-2 mutants [22810224]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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