acdh-1

Symbol: acdh-1
Name: Acyl CoA DeHydrogenase 1
Alias: dod-12
Entrez gene ID: 172358
Ensembl gene ID: C55B7.4
Species: Worm (Taxid: 6239)

Function:
short-chain fatty acid-specific acyl-CoA dehydrogenase

Observation:

RNAi knockdown of acdh-1 starting at hatching or only during the adulthood significantly decreases lifespan of eat-2 without affecting wild-type lifespan. ACDH-1 significantly upregulated in eat-2. Increased content of ACDH-1 is, at least partially, required for lifespan-extension by DR [22810224].



Interventions:
  • acdh-1 RNAi

  • Assays: Organismal Lifespan

    Classification:
  • DR-Induced
  • DR-Essential
  • No Age Effect


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • ACADSB (9606)
  • ACADSB (9598)
  • ACADSB (9615)
  • ACADSB (9913)
  • Acadsb (10090)
  • Acadsb (10116)
  • ACADSB (9031)
  • LOC100332956 (7955)
  • CG3902 (7227)
  • AgaP_AGAP009783 (7165)
  • acdh-3 (6239)
  • acdh-1 (6239)
  • GeneID:2679063 (148305)
  • NCU06543 (5141)



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