Denigma

Hsp70Bb

Symbol: Hsp70Bb
Name: Hsp70Bb Heat-shock-protein-70Bb
Entrez gene ID: 48583
Ensembl gene ID: FBgn0013278
Species: Fly (Taxid: 7227)

Function:
Heat shock response

Observation:

Overexpression of the Hsp70 locus (containing Hsp70Bb and Hsp70Bc) in transgenic flies extends lifespan as much as 7.9% [9363888].



Interventions:
  • Hsp70 locus overexpression +7.9%

    • Assays: Organismal Lifespan
    Mean: +7.9

    Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • HSPA1A (9606)
  • HSPA1B (9606)
  • HSP70 (9615)
  • HSPA1A (9913)
  • Hspa1b (10090)
  • Hspa1a (10090)
  • Hspa1b (10116)
  • LOC100333726 (7955)
  • Hsp70Ab (7227)
  • Hsp68 (7227)
  • Hsp70Aa (7227)
  • Hsp70Bc (7227)
  • Hsp70Ba (7227)
  • Hsp70Bb (7227)
  • Hsp70Bbb (7227)
  • SSA3 (4932)
  • KLLA0E20527g (28985)
  • AGOS_AER187W (33169)
  • AT3G09440 (3702)

    • Note: Hsp70Bb and Hsp70Bc locus overlap. Was original annotated with FBgn0001230

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