ESA1

Symbol: ESA1
Alias: KAT5; TAS1
Entrez gene ID: 854418
Ensembl gene ID: YOR244W
Species: Yeast (Taxid: 4932)

Functional description:
Esa1p; Catalytic subunit of the histone acetyltransferase complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression and transcriptional silencing at the rDNA locus [Source:SGD;Acc:S000005770] [Ensembl]

Observation:

esa1-531 mutant has an even shorter chronological lifespan than PKA1 deletion mutant in both 2% glucose (ad libitum) and water (extreme DR) at 30 degree Celsius, a semipermissive temperature. At the permissive temperature (25 degree Celsius) there is little difference [19303850].



Interventions:
  • ESA1 mutation

  • Assays: Chronological Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • KAT5 (9606)
  • KAT5 (9598)
  • KAT5 (9615)
  • KAT5 (9913)
  • Kat5 (10090)
  • Kat5 (10116)
  • zgc:92510 (7955)
  • htatip (7955)
  • Tip60 (7227)
  • AgaP_AGAP001539 (7165)
  • mys-1 (6239)
  • mst1 (4896)
  • ESA1 (4932)
  • KLLA0F11209g (28985)
  • AGOS_ACR138W (33169)
  • GeneID:2677551 (148305)
  • NCU05218 (5141)



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