|
Symbol: CG7834 Name: CG7834 gene product from transcript CG7834-RA Entrez gene ID: 43515 Ensembl gene ID: FBgn0039697 Species: Fly (Taxid: 7227) Functional description: CG7834 gene product from transcript CG7834-RA; This gene is referred to in FlyBase by the symbol Dmel\CG7834 (FBgn0039697). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: electron carrier activity. Based on sequence similarity, it is predicted to be involved in the biological process: oxidative phosphorylation. 3 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; Electron transfer flavoprotein, beta subunit; Electron transfer flavoprotein, beta-subunit, conserved site; Rossmann-like alpha/beta/alpha sandwich fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes. [FlyBase] Observation: Muscle specific RNAi knockdown of CG7834 which reduces its mRNA levels by 25-35%, significantly reduces the DR-dependent lifespan extension. CG7834 RNAi animals exhibit only a 14% increase compared to the 55% lifespan-increase in controls upon DR [22768842]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Inparanoids Edit \ Update (Admin) | Delete |
Comment on This Data Unit