NDT80

Symbol: NDT80
Name: Non-DiTyrosine 80
Entrez gene ID: 856524
Ensembl gene ID: YHR124W
Species: Yeast (Taxid: 4932)

Functional description:
Ndt80p; Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containing middle sporulation elements (MSE) [Source:SGD;Acc:S000001166] [Ensembl]

Observation:

Transient overexpression of NDT80 rejuvenates old cells [21700873].



Interventions:
  • NDT80 transient overexpression

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • NDT80 (4932)
  • KLLA0F24420g (28985)
  • AGOS_AGR347W (33169)



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