|
Symbol: unc-79 Name: UNCoordinated Entrez gene ID: 3565180 Ensembl gene ID: E03A3.6 Species: Worm (Taxid: 6239) Functional description: Protein UNC-79; Uncoordinated protein 79 [Source:UniProtKB/Swiss-Prot;Acc:P42173] [Ensembl]; unc-79 encodes a novel, conserved protein; unc-79 functions in a pathway with unc-77 and nca-2, which encode alpha-1 subunits of voltage-insensitive cation leak channels, to regulate locomotion and the response to specific volatile anesthetics; unc-79 exerts its effects on these processes, at least in part, by regulating the levels of UNC-77 and NCA-2 proteins; an unc-79::gfp reporter is expressed in the nervous system in ventral nerve cord neurons in L2 and L3 larvae and in one or two head neurons in adults; UNC-79 exhibits a punctate staining pattern in ventral nerve cord and nerve ring processes, and this staining is dependent upon UNC-80, UNC-77, and NCA-2. [WormBase] Observation: The unc-79(e1068) allele has no significant effect on lifespan [9789046]. unc-78 mutants display irregular movement [4366476]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
Comment on This Data Unit