Denigma

unc-78

Symbol: unc-78
Name: UNCoordinated 78
Entrez gene ID: 180631
Ensembl gene ID: C04F6.4
Species: Worm (Taxid: 6239)

Functional description:
Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Regulator of actin organization in myofibrils. [UniProt]

Observation:

Mutation in unc-78 has no effect on lifespan [9789046].

unc-78 mutants move slowly [7190524].



Interventions:
  • unc-78 mutation

    • Assays: Organismal Lifespan

    Classification:
  • No Age Effect


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • WDR1 (9606)
  • WDR1 (9598)
  • WDR1 (9615)
  • WDR1 (9913)
  • Wdr1 (10090)
  • Wdr1 (10116)
  • WDR1 (9031)
  • wdr1 (7955)
  • flr (7227)
  • AgaP_AGAP002509 (7165)
  • unc-78 (6239)
  • tag-216 (6239)
  • SPAC9G1.05 (4896)
  • AIP1 (4932)
  • KLLA0F13750g (28985)
  • AGOS_ABL043W (33169)
  • GeneID:2683019 (148305)
  • NCU03944 (5141)
  • AT3G18060 (3702)
  • Os01g0125800 (4530)



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