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Symbol: BNA6 Name: Biosynthesis of Nicotinic Acid 6 Entrez gene ID: 850608 Ensembl gene ID: YFR047C Species: Worm (Taxid: 6239) Functional description: Bna6p; Quinolinate phosphoribosyl transferase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p [Source:SGD;Acc:S000001943] [Ensembl] Observation: Deletion of BNA6 (alias QPT1) has no effect on replicative lifespan and is not required for lifespan extension by DR, but is lethal with mutation of NPT1 [11000115]. Deletion of BNA6 decreases chronological lifespan [17110466]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Note: Does BNA6 deletion really decrease chronological lifespan? Edit \ Update (Admin) | Delete |
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