MORF4

Symbol: MORF4
Name: mortality factor 4
Entrez gene ID: 10934
Species: Human (Taxid: 9606)

Functional description:
Seems to protects cells by scavenging oxidative molecules or harmful products of oxidation. [UniProt]

Observation:

Overexpression of MORF4 reverses the immortal phenotype of immortal cell lines in complementation group B [9891081]. Cellular senescence is dominant over immortality in fused hybrids of normal and immortal human cell in culture [6879195]. Fusion of immortal cell lines with each other led to the idenetification of four complementation groups for immortality [3413074]. MORF4 rescues the immortal phenotype [9891081].



Interventions:
  • MORF4 overxpression

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • MORF4 (9606)
  • GeneID:2684890 (148305)
  • NCU06787 (5141)



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