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Symbol: asg-1 Name: ATP Synthase G homolog 1 Entrez gene ID: 172673 Ensembl gene ID: K07A12.3 Species: Worm (Taxid: 6239) Functional description: Homolog of ATP synthase G required for growth at a normally high rate and normal osmoregulation; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity). [UniProt] Observation: RNA interference of asg-1 leads to lifespan extension [15998808]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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