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Symbol: dj-1beta Name: dj-1β Entrez gene ID: 43652 Ensembl gene ID: FBgn0039802 Species: Fly (Taxid: 7227) Functional description: CG1349 gene product from transcript CG1349-RA; dj-1beta [Source:FlyBase gene name;Acc:FBgn0039802] [Ensembl]; The gene dj-1β is referred to in FlyBase by the symbol Dmel\dj-1β (CG1349, FBgn0039802). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: response to oxidative stress; adult locomotory behavior. 17 alleles are reported. The phenotype of these alleles is annotated with: dopaminergic neuron. It has one annotated transcript and one annotated polypeptide. Protein features are: DJ-1; ThiJ/PfpI. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes. [FlyBase] Observation: Loss of function mutation in dj-1beta shortens maximum lifespan by 40% and results in increased sensitivity to oxidative stress and motor impairments [17651920]. Interventions: Assays: Organismal Lifespan Maximum: -40 Classification: References: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Inparanoids Edit \ Update (Admin) | Delete |
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