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Symbol: ucp2 Name: uncoupling protein 2 Entrez gene ID: 555812 Ensembl gene ID: ENSDARG00000043154 Species: (Taxid: 7955) Functional description: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat [UniProt] Observation: Overexpression of zebrafish's ucp2 in nematode increases mean, median, and maximum lifespan by 42, 40, and 26%, which is non-additive with sDR [22737090]. Interventions: Assays: Organismal Lifespan Classification: Homologs Edit \ Update (Admin) | Delete |
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