Denigma

PAN2

Symbol: PAN2
Name: Poly(A)-binding protein-dependent poly(A) riboNuclease 2
Entrez gene ID: 852786
Ensembl gene ID: YGL094C
Species: Yeast (Taxid: 4932)

Functional description:
Pan2p; Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes [Source:SGD;Acc:S000003062] [Ensembl]

Observation:

Deletion mutant of PAN2 live approximately as long as wild-type under starvation/extreme DR [20657825].



Interventions:
  • PAN2 deletion

    • Assays: Chronological Lifespan

    Classification:
  • No Age Effect


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PAN2 (9606)
  • PAN2 (9615)
  • PAN2 (9913)
  • Pan2 (10090)
  • Pan2 (10116)
  • USP52 (9031)
  • LOC792831 (7955)
  • CG8232 (7227)
  • AgaP_AGAP010626 (7165)
  • F31E3.4 (6239)
  • ubp13 (4896)
  • PAN2 (4932)
  • KLLA0E18877g (28985)
  • AGOS_AFL055W (33169)
  • GeneID:5050729 (148305)
  • NCU10733 (5141)



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