SSN2

Symbol: SSN2
Name: Suppressor of SNf1
Alias: NUT8;SCA1;SRB9;UME2;RYE3;MED13
Entrez gene ID: 852053
Ensembl gene ID: YDR443C
Species: Yeast (Taxid: 4932)

Functional description:
Ssn2p; Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation [Source:SGD;Acc:S000002851] [Ensembl]

Observation:

Although SSN2 was identified as a potential long-lived mutant strain in a bar-code screen, deletion of SSN2 does not significantly affect chronological lifespan under starvation/extreme DR [20657825].



Interventions:
  • SSN2 deletion

  • Assays: Chronological Lifespan

    Classification:
  • No Age Effect


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SSN2 (4932)
  • KLLA0B01353g (28985)
  • AGOS_AER323W (33169)



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